Payam Minoofar 457 N. Doheny Dr., Apt. 204 Beverly Hills, CA 90210 +1 310 601-8322 payam@minoofar.com SYNOPSIS Experienced scientist with * Over 9 years of work experience in industries ranging from environmental chemistry and analytical chemistry to clinical diagnostics and proteomics in the clinical setting. * Expertise in spectroscopy, materials chemistry, luminescent materials and analytical methods. * Proven ability to work in foreign countries and in foreign languages. EXPERIENCE August 2006-August 2007: APIC Corp. Los Angeles, California Development of an Explosives Detector Based on Photoacoustic Spectroscopy * Designed and chemically characterized (with gas chromatography) three preconcentrators. * Chemically characterized and integrated a commercial preconcentrator acquired from Sandia National Labs into our compact photoacoustic spectrometer which uses quantum cascade lasers. * Numerically simulated the expected output with the profile of the quantum cascade lasers (QCL). * Designed, developed and chemically characterized a vapor generator for high explosives. * Chemically characterized the final QCL photoacoustic spectrophotometer. * Developed computer algorithms for system control. * Wrote and submitted proposals for government grants, interacted with * government sponsor (DoD) and assured compliance with specifications of contract. April 2004-August 2007: John Wayne Cancer Institute. Santa Monica, CA. Proteomic Analysis of Primary Hyperparathyroidism * Microtomed, stained and performed laser capture microdissection (LCM) on human tissue. * Processed and obtained the surface enhanced laser desorption ionization (SELDI, a modified MALDI method) mass spectra of captured cells. * Analyzed results with classification and regression trees (CART). * Leading the collaboration with Drs. Armando Giuliano (John Wayne Cancer Institute), Dave S. Hoon (John Wayne Cancer Institute) and Martin Eisenacher (Ruhr UniversitŠt Bochum, Germany). November 2004-December 2005: van't Hoff Institute for Molecular Sciences. Universiteit van Amsterdam, The Netherlands, and Wesfaelische Wilhelms-Universitaet Muenster, Germany. Spectroscopic Characterization of Luminescent Materials and Devices. * Steady-state spectroscopy, transient absorption and fast (pico- and femtosecond) dynamics of luminescent materials (small organic molecules, cyclometalated Iridium complexes, fluorescent supramolecular zinc assemblies, and conducting polymers) designed for higher efficiency electroluminescent devices. * Fabrication and spectroscopic characterization of electroluminescent devices (sponsored by Philips Electronics). * Quantum chemical (Gaussian 03) treatment of the electronic structures of cyclometalated iridium complexes. * In collaboration with Professors Michael Schmittel (Uni-Siegen, Germany), Gianluca Farinola (Uni-Bari, Italy) and Drs. Igor Avilov and Jerome Cornil (Universite Mons-Hainaut, Belgium). September 1998-February 2004: Department of Chemistry and Biochemistry. University of California, Los Angeles. Synthesis and Characterization of Doped, Nanostructured Silicate Sol- Gel Thin Films and Bulk Sol-Gel Materials. Jeffrey I. Zink, Ph.D., Research Advisor * Synthesized nanostructured silicate sol-gel thin films containing europium complexes, laser dyes, and a water soluble polyparaphenylinevinylene. * Designed, synthesized and characterized functional sol-gel thin films: thin films in which selective placement of luminescent dopants transported energy from one region to another region through resonance energy transfer (RET). Deduced information about the location of the dopants and their distribution in the films from quantitation of energy transfer according to the Foerster model. * Characterized luminescent, mesostructured silicate thin films with x-ray diffraction, luminescence, excitation and UV-Vis absorption spectroscopy with conventional and laser light sources, and time domain and frequency domain luminescence lifetime measurements. * Performed two-photon photodeposition of gold nanoparticles in sol-gel matrices. * Designed and constructed a humidity control chamber for improved film synthesis. * Characterized luminescent vaults (eucaryotic ribonucleoprotein particles). * Collaborations with Professors Bruce Dunn (UCLA Dept. of Materials Science) and Lenny Rome (UCLA School of Medicine). April 1996-Sept. 1998: Causes and Treatments of Disorders of Bone Metabolism. John Wayne Cancer Institute. Santa Monica, California. * Carried out and oversaw the completion of a study of the efficacy of salmon calcitonin therapy in the treatment of human osteoporosis for Sandoz Pharmaceuticals (now Novartis). Duties included performing radioimmunoassays on patient serum specimens supplied to our lab from 50 research centers in the US and Europe, gathering and statistical analysis of data, reporting the data, and acting as a liaison between the research centers. * Conducted a study of the relationship between declining testosterone levels in elderly men and prostate cancer patients and the increased incidence of osteoporosis in those populations. * Supervised the development of a new test of parathyroid gland function. Manuscript to be submitted. * Served as site coordinator for a clinical trial of a bisphosphonate patch in Paget's disease of bone patients for Novartis Pharmaceuticals. * Contributed to the implementation of bone density measurements by computed tomography at St. John's Hospital, Santa Monica, CA. 1994-1995: Toxicology of Drugs and Pesticides McGaw, Inc. Irvine, California. * Performed liquid and solid phase extraction of radiolabeled drug and pesticide metabolites from plant and animal tissue. * Developed methods, characterized and identified metabolites through HPLC and GC-MS in compliance with GLP guidelines as part of toxicology studies required by the FDA and EPA. * Prepared reports. 1989-1991: Synthesis of Natural Product Analogs. Department of Chemistry. University of California, Berkeley. * Carried out reactions in the total synthesis of inositol triphosphate analogs via Diels-Alder reaction with activated dienes, radical chemistry on sugars, and synthesis from 1,4-cyclohexadiene. EDUCATION * Doctor of Philosophy, Inorganic Chemistry, University of California, Los Angeles. February 2004 Dissertation "Confinement of Luminophores in Mesostructured Sol-Gel Thin Films: Deliberate Placement of Lanthanides and Laser Dyes and Quantitation of Energy Transfer" Jeffrey I. Zink, Advisor. * Bachelor of Science, Chemistry, University of California, Berkeley. May 1992 OTHER WORK EXPERIENCE January 2006 Development of an Introductory Manual to Programming for Scientists. Wavemetrics, Inc. Portland Oregon. * Authored an introductory programming manual for the data processing software IGOR Pro. Teaching Assistant Department of Chemistry, University of California, Los Angeles. September 1998-June December 2001 * Prepared and delivered lectures, devised, proctored and graded exams and quizzes in general, organic, and advanced inorganic chemistry discussion sections of 10 to 30 students. * Taught and organized courses in general and organic laboratory techniques. * Instructed the use of HPLC, GC-MS, XRF, and AA spectrometry methods and the theory and application of statistical analysis in an advanced instrumental analysis laboratory course. * Mentored three undergraduate students in independent research. OTHER SKILLS * Proficiency with all major productivity software packages; programming IGOR Pro for data analysis, visualization and presentation. Programming experience in other BASIC and Pascal. * Fluent in Farsi, intermediate French and German, some proficiency in * Hebrew. INVITED LECTURES * "Following primary hyperparathyroidism from surgery to proteomic analysis", 3rd Muenster Conference on Single Cell Analysis, December 5, 2006, Muenster, Germany. PUBLICATIONS * Avilov, I.; Minoofar, P.; Cornil, J.; De Cola, L. "Influence of substituents on the energy and nature of the lowest excited state of heteroleptic phosphorescent Ir(III) complexes: a joint theoretical and experimental study" Journal of the American Chemical Society, 2007, 129(6), 8247-8258. * Kickhoefer, V.; Garcia, Y.; Mikyas, Y.; Johansson, E.; Zhou, J.; Raval-Fernandes, S.; MINOOFAR, P.; Zink, J.; Dunn, B.; Stewart, P.; Rome, L. "Engineering of vault nanocapsules with enzymatic and fluorescent properties" Proceedings of the National Academy of Sciences, 2005, 102(12), 4348-4352. * MINOOFAR, P.; Dunn, B.; Zink, J. "Multiply Doped Nanostructured Silicate Sol-Gel Thin Films: Spatial Segregation of Dopants, Energy Transfer, and Distance Measurements" Journal of the American Chemical Society, 2005, 127(8), 2656-2665. * MINOOFAR, P; Hernandez, R.; Franville, A.; Chia, S.; Dunn, B.; Zink, J. "Strategies for spatially separating molecules in mesostructured sol-gel silicate films" Journal of Sol-Gel Science and Technology, 2003, 26(1-3), 571. * Garcia-Macedo, J. A.; Valverde; Cruz, D.; Franco, A.; Zink; J. I.; MINOOFAR, P. "Structure and Polyphenylenevinylene Concentration Effect on the Photoconductivey Response from Mesostructured Silica Films" Journal of Physical Chemistry B, 2003, 107, 2249-2252. * MINOOFAR, P.; Franville, A.; Chia, S.; Hernandez, R.; Dunn, B.; Zink, J. "Placement and Characterization of Pairs of Luminescent Molecules in Spatially Separated Regions of Nanosctructured Thin Films" Journal of the American Chemical Society, 2002, 124(48), 14388. * Hernandez, R.; Franville, A.; MINOOFAR, P.; Dunn, B.; Zink, J. "Controlled Placement of Luminescent Molecules and Polymers in Mesostructured Sol-Gel Thin Films" Journal of the American Chemical Society, 2001, 123, 1248. * Singer, F.; MINOOFAR, P. "Bisphosphonate Therapy of Osteoporosis" in The Osteoporosis Primer, Henderson, J., Goltzman, D., Eds., Cambridge University Press: New York, 2000. * Singer, F.; MINOOFAR, P. "Bisphosphonates in the Treatment of Disorders of Mineral Metabolism" Advances in Clinical Endocrinology and Metabolism, 1995, 6, 259. PRESENTATIONS * Garcia-Macedo, J. A.; Cruz, D.; Valverde, G.; Zink, J.I.; Hernandez, R.; MINOOFAR, P. "Charge transport under illumination in mesoporous continuous films." Proceedings of SPIE-The International Society for Optical Engineering, 2002, 4465(Organic Photovoltaics II): 137-142. * MINOOFAR, P.; Zink, J. I. "Multiple Inclusion and Energy Transfer in Mesostructured Sol-Gel Thin Films", Poster presented at the meeting of the Materials Research Society, April 2002, San Francisco, California. REFERENCES Judith Meester, Lumera Corporation, +1 425 398 6590, jmeester@lumera.com Frederick R Singer, M.D., +1 582 7117, fsinger@ucla.edu Professor Jeffrey I Zink, +1 825 1001, zink@chem.ucla.edu Professor Luisa De Cola, +49 251 980 2873, decola@uni-muenster.de Dr. Axel Herzog, DuPont, +1 302 695 4326, Axel.Herzog@usa.dupont.com Dr. Bradley Kirsch, The Clorox Company, +1 925 425 6743, bradley.kirsch@clorox.com Dr. Olivier Enger, BASF AG, +49 621 60 91436